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MaineHealth Institute for Research

Ranked among the nation’s top 100 integrated healthcare delivery networks, MaineHealth is a 10-hospital statewide integrated not-for-profit health care delivery system leading the way in promoting public health and wellness in Maine. The system spans eleven counties, and serves approximately three-fourths of Maine’s population of 1.3 million as well as one county in rural New Hampshire. Maine Medical Center, the state’s largest hospital, academic and tertiary medical center, and a leading teaching hospital in Northern New England, serves as the flagship hospital for MaineHealth. The MaineHealth Institute for Research oversees a broad array of dynamic research programs and provides a strong research infrastructure to support investigators. Major Research Centers include:  The Center for Molecular Medicine, a nationally-recognized basic biomedical research program; Center for Clinical and Translational Science, which brings together basic and clinical investigators to launch translational projects and works to expand clinical studies throughout MaineHealth; Center for Interdisciplinary Population and Health Research, a program focusing on patient-centered outcomes, health disparities, population health, and health services research. Facilities and resources in each center are summarized below.

The Center for Molecular Medicine is housed in an 80,000ft2 research facility located on a 50-acre campus in Scarborough, Maine that houses clinical, rehabilitation, diagnostic, and research space. This basic science division is comprised of 19 Principal Investigators and a staff of ~120. The research focus is on vascular disease, cancer biology, diabetes, aging, bone metabolism, and stem cell biology. The building contains wet laboratories, a mouse barrier facility, shared core facilities and equipment, and five conference rooms, all equipped with state-of-the-art video-conferencing capabilities conducive to collaborative interactions.

 The Center for Clinical and Translational Science is a multi-disciplinary scientific community linking basic, clinical and translational investigators to collaborate on research across the translational research spectrum. It provides an environment for translational research to flourish by providing research training, education, guidance and mentorship to new translational investigators as well as research support and services such as informatics, team science, data science support, and research navigation services. Resources include REDCap and the Observational Medical Outcomes Partnership research data warehouse. Infrastructure and support for clinical and translational research include our NIH-funded Northern New England Clinical and Translational Research Network, the National COVID Cohort Collaborative, and Research COVID to Enhance Recovery programs.

The Center for Interdisciplinary Population and Health Research staff and investigators design and conduct innovative research and evaluation to understand and improve population health. Efforts focus on patient-centered outcomes, working with communities, addressing health disparities, and building infrastructure to conduct and disseminate research and interventions within MaineHealth and across the state through education, training, and mentoring. Areas of research include biobehavioral cancer research, community engagement and health disparities, pediatrics, emergency medicine, infectious disease, and clinical and population health.