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Current Investigator Research

Catalysis of early metabolic pathways as a form of hereditary during a possible emergence of life from hydrothermal vents

Catalysis of early metabolic pathways as a form of hereditary during a possible emergence of life from hydrothermal vents

Investigator: Reuben Hudson, Ph.D., College of the Atlantic Project Summary Carbon fixation to simple organic building blocks, and the subsequent increases in molecular complexity underpins countless universal cellular processes. This study...
Determining the role of calcium on the mitochondrial unfolded protein response

Determining the role of calcium on the mitochondrial unfolded protein response

Investigator: Suzanne Angeli, Ph.D., University of Maine Project Summary The opening of the mitochondrial permeability transition pore (mPTP) is associated is associated with aging and numerous age-related diseases. This proposal examines the...
Functional role of protein secretion systems shared among Paraburkholderia symbionts of social amoebas

Functional role of protein secretion systems shared among Paraburkholderia symbionts of social amoebas

Investigator: Suegene Noh, Ph.D., Colby College Project Summary Our goal is to better understand how and why fitness outcomes differ among hosts when they encounter the same microbial symbiont in social groups. The amoeba Dictyostelium discoideum...
Identification of neural and epigenetic biomarkers for affective dysfunction following early adversity

Identification of neural and epigenetic biomarkers for affective dysfunction following early adversity

Investigator: Jennifer Honeycutt, PhD, Bowdoin College An individual’s early life environment plays a central role in shaping developmental trajectories, and therefore confers substantial influence on later-life physical and mental health outcomes. A...
Understanding the mechanisms of MMS21 in genome instability through mutations in Saccaramyces cerevisiae and human

Understanding the mechanisms of MMS21 in genome instability through mutations in Saccaramyces cerevisiae and human

Investigator: Yee Mon Thu, PhD, Colby College Genome instability describes a condition in which the accuracy of genetic information or structural integrity of the genome is compromised. Under such a condition, the DNA molecule may be chemically...